@article{Houang1997SuccessfulTO,
title={Successful Treatment of Four Patients With Recalcitrant Vaginal Trichomoniasis With a Combination of Zinc Sulfate Douche and Metronidazole Therapy},
author={Elizabeth T S Houang and Z Ahmet and Adam G. Lawrence},
journal={Sexually Transmitted Diseases},
year={1997},
volume={24},
pages={116–119}
}Background and Objectives: There is no certain cure available for patients suffering from recalcitrant trichomoniasis. Zinc sulfate is reported to have antitrichomonal properties. We report our experience in treating four patients empirically with a combination of zinc sulfate douche and metronidazole. Study Design: A retrospective case analysis. Patients who presented to the tertiary referral clinic with chronic recurrent trichomoniasis without evidence of reinfection were treated empirically… Show 20 CitationsManaging resistant Trichomonas vaginitis
Treatment of metronidazole-resistant trichomoniasis is mainly limited to case reports or series and promising options include oral tinidazoles and topical paromomycin cream. ReferencesSHOWING 1-10 OF 10 REFERENCES Petrin D, Delgaty K, Bhait R, Garber G: Clinical and microbiological aspects of Trichomonas vaginalis. Clin Microbiol Rev 1998, 11:300–317. Very thorough basic science and clinical overview of infections caused by T. vaginalis. PubMed CAS Google Scholar Lossick JG, Kent HL: Trichomoniasis: trends in diagnosis and management. Am J Obstet Gynecol 1991, 165:1217–1222. PubMed CAS Google Scholar Cotch MF, Pastorek JG, Nugent RP, et al.: Vaginal Infections and Prematurity Study Group: demographic and behavioral predictors of Trichomonas vaginalis infection among pregnant women. Obstet Gynecol 1991, 78:1087–1092. 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Article CAS PubMed Google Scholar Houang ET, Ahmet Z, Lawrence AG: Successful treatment of four patients with recalcitrant vaginal trichomoniasis with a combination of zinc sulfate douche and metronidazole therapy. Sex Transm Dis 1997, 24:116–119. PubMed CAS Article Google Scholar Sears SD, O’Hare J: In vitro susceptibility of Trichomonas vaginalis to 50 antimicrobial agents. Antimicrob Agents Chemother 1988, 32:144–146. PubMed CAS Google Scholar Pattman RS, Sprott MS, Kearns AM, Earnshaw M: Failure of mebendazole to cure trichomonal vaginitis resistant to metronidazole: case reports. Genitourin Med 1989, 65:274–275. PubMed CAS Google Scholar Wong CA, Wilson PD, Chew TA: Povidone-iodine in the treatment of metronidazole-resistant Trichomonas vaginalis. Aust N Z J Obstet Gynaecol 1990, 30:169–171. PubMed CAS Google Scholar Livengood CH III, Lossick JG: Resolution of resistant vaginal trichomoniasis associated with the use of intravaginal nonoxynol-9. Obstet Gynecol 1991, 78:954–956. PubMed Google Scholar British Co-Operative Clinical Group: An investigation, by questionnaire, of cases of recalcitrant vaginal trichomoniasis seen in genitourinary medicine clinics in the United Kingdom. Int J STD AIDS 1992, 3:24–27. Google Scholar Voolman T, Boreham P: Metronidazole resistant Trichomonas vaginalis in Brisbane. Med J Aust 1993, 159:490. Google Scholar Hamed KA, Studemeister AE: Successful response of metronidazole-resistant trichomonal vaginitis to tinidazole. Sex Transm Dis 1992, 19:339–340. PubMed CAS Article Google Scholar Nyirjesy P, Weitz MV, Gelone SP, Fekete T: Paromomycin for nitroimidazole-resistant trichomonosis. Lancet 1995, 346:1110. PubMed Article CAS Google Scholar Nyirjesy P, Sobel JD, Weitz MV, et al.: Difficult to treat trichomoniasis: results with paromomycin cream. Clin Infect Dis 1998, 26:986–988. Case series reviewing experience with paromomycin cream in cases in which metronidazole resistance or allergy was present PubMed CAS Google Scholar Spitzbart H: Ist Paromomycin zur Behandlung der Trichomonaden-Infecktion bei der Frau geeignet? II: Klin Erfahrungen. Zentralbl Gynakol 1966, 88:563–566. PubMed CAS Google Scholar Pearlman MD, Yashar C, Ernst S, Solomon W: An incremental dosing protocol for women with severe vaginal trichomoniasis and adverse reactions to metronidazole. Am J Obstet Gynecol 1996, 174:934–936. PubMed Article CAS Google Scholar Kurohara ML, Kwong FK, Lebherz TB, Klaustermeyer WB:Metronidazole hypersensitivity and oral desensitization. J Allergy Clin Immunol 1991, 88:279–280. PubMed Article CAS Google Scholar Can you get rid of trich naturally?There's aren't any proven home treatments for trichomoniasis. Plus, this STI often doesn't cause symptoms, so it's hard to gauge whether home treatments are effective. It's best to err on the side of caution and see a healthcare provider for any potential STIs.
What STD does metronidazole treat?Trichomoniasis is usually treated quickly and easily with antibiotics. Most people are prescribed an antibiotic called metronidazole, which is very effective if taken correctly. You'll usually have to take metronidazole twice a day, for 5 to 7 days.
Can boric acid cure trichomoniasis?As an antimicrobial, boric acid has been shown to be effective in killing the bacteria that causes trichomoniasis in vitro (Brittingham & Wilson, 2014).
How long does it take for trichomoniasis to go away after treatment?You're typically cured in about 7 to 10 days, but check with your doctor to know for sure. It's not uncommon for people to get another trich infection a few months after treatment. So make sure you don't have sex again until you and your sex partners are cured and your symptoms are gone.
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