Glossopharyngeal neuralgia (GPN) is a rare condition that can cause sharp, stabbing, or shooting pain in the throat area near the tonsils, the back of the tongue or the middle ear. The pain occurs along the pathway of the glossopharyngeal nerve, which is located deep in the neck. It serves the back of the tongue, throat and the parotid gland (one of the salivary glands) the middle ear and eustachian tube. Show
OverviewWhat is glossopharyngeal neuralgia (GPN)?Glossopharyngeal neuralgia (GPN) is a rare condition that can cause sharp, stabbing, or shooting pain in the throat area near the tonsils, the back of the tongue or the middle ear. The pain occurs along the pathway of the glossopharyngeal nerve, which is located deep in the neck. It serves the back of the tongue, throat and the parotid gland (one of the salivary glands), the middle ear and eustachian tube. Painful episodes are usually intermittent, lasting from a few seconds to a few minutes. The pain might recur several times in a day. In other cases it might not come back for several weeks or months. Certain activities may trigger painful episodes, including:
Sometimes people with this condition may avoid eating, drinking or chewing because they fear that these activities may trigger a painful attack. Over time, this can result in weight loss. Generally, only one side of the head is affected by GPN. The glossopharyngeal nerve has several branches, including the tympanic branch that receives sensations from the middle ear and mastoid. Another important branch is the carotid sinus nerve that serves the carotid body and carotid sinus (widening of a carotid artery at the main branch point). Painful attacks may result in life-threatening symptoms, such as fainting (syncope), slow heartbeat (bradycardia) or arrhythmia (irregular heartbeat). In very rare cases, cardiac arrest may occur with no painful episodes. How common is glossopharyngeal neuralgia (GPN)?The disorder is rare, with less than 1 case reported per year among 100,000 people in the United States. It tends to occur more often in adults over age 40, but it may be present at any age. It appears to affect men more than women. Symptoms and CausesWhat causes glossopharyngeal neuralgia (GPN)?Often there is no apparent cause for the condition. Compression of the glossopharyngeal nerve by a blood vessel near the brainstem may irritate the nerve and cause pain. In other cases, an elongated styloid process (a bone in the neck near the nerve) can cause pain. This condition is called Eagle syndrome. Trauma due to an injury or a surgical procedure may also result in glossopharyngeal neuralgia. Other possible causes include infections, tumors and vascular abnormalities. Patients with multiple sclerosis may experience glossopharyngeal neuralgia as a result of the breakdown of the myelin sheath, the fatty membrane that surrounds and insulates the nerve. Diagnosis and TestsHow is glossopharyngeal neuralgia (GPN) diagnosed?The location of the pain is important in the diagnosis of glossopharyngeal neuralgia, since other conditions, such as trigeminal neuralgia, may produce similar symptoms. There is no single diagnostic test that can confirm that GPN is present. An ear, nose and throat physician will perform an examination to rule out other disorders. The physician may stimulate certain areas, such as the tonsils or back of the tongue, to see if pain occurs. The doctor will ask whether certain activities, such as talking or chewing, trigger pain. An MRI (magnetic resonance imaging) or CT (computed tomography) scan may be ordered to determine whether a tumor or blood vessel is compressing the nerve. Management and TreatmentHow is glossopharyngeal neuralgia (GPN) treated?In most situations, anticonvulsant drugs are the first line of treatment. If drug therapy is not effective or if a patient has troublesome side effects from the medication, surgery is considered. Medications
Surgery Several surgical procedures may be options in alleviating the pain associated with GPN. The most common of these is microvascular decompression as explained below. If a tumor is found compressing the nerve or if Eagle syndrome is diagnosed (elongated styloid compressing the nerve), then a different type of surgery may be warranted.
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When I swallow one side of my throat and ear hurts?Pain on one side of your throat after swallowing could be the result of nerve pain from glossopharyngeal neuralgia. This condition can occur on one side in the ears, back of the tongue, tonsil, or in the jaw. This is a rare condition that can cause attacks of sudden and severe pain.
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